Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase

Authors
Kasirajan, V Smedira, NG Perl, J McCarthy, PM
Citation
V. Kasirajan et al., Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase, ANN THORAC, 67(4), 1999, pp. 1148-1150
Citations number
11
Categorie Soggetti
Cardiovascular & Respiratory Systems","Medical Research Diagnosis & Treatment
Journal title
ANNALS OF THORACIC SURGERY
ISSN journal
00034975 → ACNP
Volume
67
Issue
4
Year of publication
1999
Pages
1148 - 1150
Database
ISI
SICI code
0003-4975(199904)67:4<1148:CEAWLV>2.0.ZU;2-P
Abstract
A patient with a bioprosthetic aortic valve sustained a cerebral embolism d uring support with an implantable left ventricular assist device. This was lysed with intraarterial urokinase with complete resolution of the neurolog ical deficit. Subsequently the patient underwent heart transplantation and remains neurologically intact. This case report is the first successful use of thrombolysis for cerebral embolism associated with a mechanical assist device.