Hepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor - A case report

A 42-year-old woman was hospitalized for severe hypoglycemic coma. She had a voluminous hepatic metastasis and multiple small lung metastases from a m eningeal hemangiopericytoma initially operated on 11 years earlier. High bl ood levels of an abnormal form of insulin-like growth factor type 2 (IGF II ) associated with low blood levels of insulin, growth hormone, IGF I, and I GF BP3 were observed. After surgical resection of the liver and pulmonary m etastases, serum observed. After surgical resection of the liver and pulmon ary metastases, serum glucose levels and hormonal abnormalities returned to normal. Cancer 1999;85: 2245-8, (C) 1999 American Cancer Society.