The developement and improvement of the cryosurgical technique in combinati
on with intraoperative ultrasonographic imaging enables reliable destructio
n of liver tumors - although not free of complications - given that tried a
nd tested rules of cryosurgical research are obeyed. In this respect, we ca
n speak of real progress. On the basis of a 3-year testing phase with the C
RYO6 cryosurgical apparatus from ERBE, a protocol for the cryosurgical tech
nique for liver tumors is introduced. The spectrum of indications for cryos
urgery includes the destruction of irresectable hepatic secondaries or prim
ary tumors with curative intention and the freezing of insufficient or inco
mplete resection margins. The preliminary results of this treatment modalit
y are encouraging. However, there remains a need for further clinical resea
rch to allow final judgement of the cryosurgical method.