In this paper regulation theory is reexamined in order to further its metho
dological programme in the area of regional studies. The complex and many-s
ided determinants of regional development are brought together in a regulat
ionist conceptual framework which emphasizes the socioeconomic patterns of
interaction, interfirm linkages and industrial labour relations, supportive
institutions, and politics in a region. This conceptual framework for regi
onal studies gives key importance to the regions' institutional resources a
nd the differentiation of regional systems of regulation. From the point of
view of a regulationist approach, the quality of a region's system of regu
lation and the degree of coherence achieved in its development configuratio
n can be seen as a foundation for the region's development potential.