Em. Stipkovits et al., Electronystagmographic changes in patients with unilateral vestibular schwannomas in relation to tumor progression and central compensation, EUR ARCH OT, 256(4), 1999, pp. 173-176
Vestibular function was studied in a group of 121 patients with unilateral
vestibular schwannomas who were referred to University Hospital Utrecht bet
ween 1986 and 1996. Testing included the caloric test, torsion test, saccad
e rest, smooth pursuit test and the registration of spontaneous nystagmus.
Each patient's symptoms were taken from a chart review. The size of the tum
or was expressed as the maximum extrameatal diameter in the axial plane par
allel to the petrous ridge as seen in magnetic resonance imagine or compute
d tomography. Large tumors were significantly more often accompanied by a m
ore severe paresis on caloric testing, a smaller gain on torsion testing, s
pontaneous nystagmus, an abnormal saccade test and an abnormal smooth pursu
it test. The presence of spontaneous nystagmus was significantly more frequ
ently combined with an abnormal smooth pursuit and saccade test. There was
a significant correlation between the slow component's velocity of the spon
taneous nystagmus and the size and progression of tumor. However, a specifi
c relation between tumor size and central vestibular compensation could not
be demonstrated.