M. Ashraf-khorassani et al., A unified sample preparation system for extraction of various analyte/matrix combinations, HRC-J HIGH, 22(5), 1999, pp. 271-275
A supercritical fluid extraction/enhanced solvent extraction system (SFE/ES
E) was used to remove polar and non-polar analytes from various matrices. E
xtraction of environmental pollutants from soil, additives from low density
polyethylene, sulfa drugs from animal tissue, and drug from tablet was per
formed using both SFE and ESE. Results showed that a single instrumental sy
stem can be used to perform both ESE with organic solvents and SFE with car
bon dioxide-based fluids, Each method has its own unique advantages and app
lications. The ability to carry out both solvent extraction and supercritic
al fluid extraction with one system has obvious economical advantages.