Clarithromycin associated with torsades de pointes

Authors
Kamochi, H Nii, T Eguchi, K Mori, T Yamamoto, A Shimoda, K Ibaraki, K
Citation
H. Kamochi et al., Clarithromycin associated with torsades de pointes, JPN CIRC J, 63(5), 1999, pp. 421-422
Citations number
8
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
ISSN journal
00471828 → ACNP
Volume
63
Issue
5
Year of publication
1999
Pages
421 - 422
Database
ISI
SICI code
0047-1828(199905)63:5<421:CAWTDP>2.0.ZU;2-K
Abstract
Two cases of QT prolongation and torsades de pointes (TdP) are presented. T he patients had been taking clarithromycin (400 mg/day) for respiratory dis ease. Although erythromycin is reportedly associated with TdP, this is the first report of clarithromycin associated with TdP in the absence of other drugs already known to produce QT prolongation.