Vy. Kuperman et Mt. Alley, Differentiation between the effects of T-1 and T-2* shortening in contrast-enhanced MRI of the breast, J MAGN R I, 9(2), 1999, pp. 172-176
The purpose of this study is to describe a technique for magnetic resonance
imaging (MRI) that can potentially improve identification of malignant tis
sue in the human breast. The suggested MRI technique is based on the differ
entiation between two competing effects leading to opposite changes in imag
e intensity, namely, T-1 and T-2* shortening caused by administration of ga
dolinium chelate. The proposed approach also allows calculation of changes
in the R-2* relaxation rate in breast tissue, The feasibility of the techni
que for in vivo MRI and increased lesion contrast is demonstrated. The resu
lts indicate that this technique may improve detection of malignant breast
tissue. J, Magn. Reson, Imaging 1999;9:172-176, (C) 1999 Wiley-Liss, Inc.