In comparison with the conventional three-dimensional multiple overlapped t
hin slab acquisition (MOTSA) for magnetic resonance angiography (MRA), we h
ave developed a novel sliding interleaved k(Y) (SLINKY) acquisition techniq
ue, which can eliminate the slab boundary artifact (SBA) or venetian blind
artifact without any a priori knowledge of blood now. This work addresses t
he systematic assessment and evaluation of the SLINKY technique and verifie
s the advantages of SLINKY in the following several aspects: (a) scan time
efficiency; (b) signal-to-noise ratio (SNR), and signal-difference-to-noise
ratio (SDNR); (c) sensitivity to now velocity range; (d) sensitivity to no
w direction; (e) signal loss in slow/reversal flow regions; and (f) reconst
ruction efficiency and feasibility. Both phantom and in vivo experiments ve
rify the clinical significance of the technique. The new MRA images acquire
d with this imaging technique in 31 volunteer/patient examinations show hig
hly reliable mapping of vascular morphology without the SEA and reduction o
f signal voids in complex/slow now regions.