Preparation, crystal structure and properties of [{MnL(phen)(2)}(ClO4)center dot 1.25H(2)O](n) [HL = N-(1-carboxypropionyl)aminopyridine; phen = o-phenanthroline]

The Mn(II) complex with o-phenanthroline [MnL(phen)(2)](ClO4). 1.25H(2)O(HL = N-(1-carboxypropionyl)aminopyridine; phen = o-phenanthroline), was prepa red and crystallographically characterized. The complex consists of a six-c oordinate manganese(II) ion chelated by two bidentate carboxylato oxygen an d four o-phenanthroline nitrogen atoms. The average Mn-O and Mn-N bond leng ths are 2.229(3) and 2.254(3) Angstrom and 2.210(4)-2.250(3) Angstrom, resp ectively. The intermolecular hydrogen bonding interaction O(1)... N(5a) giv es rise to crystal packing determined by an infinite chain along the a axis . Preliminary pharmacological tests demonstrated that this Mn(II) complex s howed definite inhibition activity against B. subtilis 6633, S. lutea, S. a ureus 209p, P. diplococcus, C. Albicans (Robin) Berkh 50, S. Sake Yake and P388 in vitro.