Synthesis of tetracyclic and pentacyclic phenothiazines via benzotriazole methodology

Authors
Katritzky, AR Agamy, S Yang, BZ Qiu, GF
Citation
Ar. Katritzky et al., Synthesis of tetracyclic and pentacyclic phenothiazines via benzotriazole methodology, J HETERO CH, 36(2), 1999, pp. 473-476
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
36
Issue
2
Year of publication
1999
Pages
473 - 476
Database
ISI
SICI code
0022-152X(199903/04)36:2<473:SOTAPP>2.0.ZU;2-K
Abstract
Treatment of 10-(benzotriazol-1-yl)alkylphenothiazine with electron-rich al kenes in the presence of zinc bromide gave tetracyclic phenothiazines 4 and 9 as well as pentacyclic phenothiazines 5, which have potential use in the pharmaceutical industry.