Synthesis and spectral properties of 5-methylthio-4H-1-(p-substituted-phenyl)-3a-(p-substituted-phenyl)-9-[(m-; and p-substituted)-phenoxy]-3a,4-dihydro[1,2,4]oxadiazolo[4,5-a][1,5]benzodiazepin
Ec. Cortes et al., Synthesis and spectral properties of 5-methylthio-4H-1-(p-substituted-phenyl)-3a-(p-substituted-phenyl)-9-[(m-; and p-substituted)-phenoxy]-3a,4-dihydro[1,2,4]oxadiazolo[4,5-a][1,5]benzodiazepin, J HETERO CH, 36(2), 1999, pp. 477-480
The preparation of eight novel substituted [1,2,4]oxadiazolo[4,5-a] [1,5]be
nzodiazepines which have potentially useful pharmacological properties; by
1,3-cycloaddition of benzonitrile oxides, generated in situ from benzohydro
xamoyl chloride and triethylamine, to 1,5-benzodiazepine derivatives is des
cribed. The structure of all products was corroborated by ir, H-1-nmr, C-13
-nmr and ms.