Dihydrothienopsoralens: New furocoumarins as potential photoreacting agents

Authors
Zoubir, B Refouvelet, B Aubin, F Humbert, P Xicluna, A
Citation
B. Zoubir et al., Dihydrothienopsoralens: New furocoumarins as potential photoreacting agents, J HETERO CH, 36(2), 1999, pp. 509-513
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
36
Issue
2
Year of publication
1999
Pages
509 - 513
Database
ISI
SICI code
0022-152X(199903/04)36:2<509:DNFAPP>2.0.ZU;2-T
Abstract
A series of new dihydrothienopsoralen derivatives were synthesized from 6-h ydroxybenzo[b]furan in four steps in good yield. These compounds were prepa red as potential photosensitizing and chemotherapeutic agents for psoriasis . The spectroscopy study in also reported and showed an absorbance at lambd a = 364 nm and fluorescence at lambda = 440 nm with high molar absorptivity , wave length used to perform the photochemical and photobiological experim ents.