A new procedure for the automatic generation of finite element meshes of bo
ne segments from computed tomography (CT) data self is described. The new m
ethod allows a direct automatic generation from the CT data and produces a
very accurate unstructured hexahedral mesh. The accuracy of the method was
established using the CT images of an artificial femur showing range of att
enuation values comparable to those of a human femur. To establish the opti
mal values for the parameters controlling the mesh a sensitivity analysis w
as carried out using mesh-conditioning indicators. Some of the best mashes,
with increasing levels of refinement, were wed to analyse the stresses ind
uced in the proximal femur by single leg stance posture. The accuracy of th
e meshes was evaluated using an implicit a posteriori residual-based error
estimates. The number of elements with stress residuals larger than 10% of
the peak stress was 7.8% using the coarsest mesh and only 1.8% with the fin
est mesh. The proposed method has been proved able to conjugate full automa
tion with high-quality finite element meshes. The stress predictions obtain
ed wing these hexahedral-only mashes have been more accurate than those obt
ained by any other automatic mesh generation algorithm. Once properly integ
rated in an easy-to-use application the described method could finally make
feasible many clinical applications of finite element analysis.