Eleven patients with active unicameral bone cysts were treated primarily wi
th placement of demineralized bone matrix in the cyst by using a two-needle
technique and a custom large-bore needle. Cyst healing was rated according
to the Neer classification, and the average time of healing was 4.5 months
. The demineralized bone matrix demonstrated an ability to obliterate the c
yst in nine of 11 patients by using a single injection within 4-5 months, a
nd at 2 years' follow-up, no cysts were deemed active or recurrent.