Postoperative fever in the pediatric orthopaedic population remains a clini
cal concern even though prior studies concluded that fevers are a poor pred
ictor of surgical complications. In this retrospective study of 177 patient
s, we established guidelines regarding the degree and time course of fever
we should expect based on the perioperative conditions of magnitude of surg
ery, duration of surgery, need for intraoperative transfusion, estimated bl
ood loss, age, and gender. To provide a more sensitive assessment of fever,
we developed composite temperature curves for each patient and defined the
area under these curves as the total febrile response (TFR). This allowed
us to assess fever as a cumulative event, taking into account both its magn
itude and duration. A multivariate model then determined that of the periop
erative conditions studied, intraoperative transfusion status and estimated
blood loss were most helpful in predicting a patient's TFR. The results of
this study can be used as an additional tool for assessing postoperative p
rogress and whether a fever is within the normal limits indicated by a pati
ent's perioperative variables.