Orf is an occupational dermatosis caused by a poxvirus that infects sheep o
r goats. Human transmission typically occurs in people in contact with the
infected animals or by handling contaminated animal products such as wool o
r meat. The infection in humans is classically characterized by a solitary
papule on the fingers or hands. Involvement of the face or head has rarely
been reported. We report orf in a young woman with multiple nodules on the
face.