The synthesis of 1,8-dihydroxynaphthalene-derived natural products: palmarumycin CP1, palmarumycin CP2, palmarumycin C-11, CJ-12,371, deoxypreussomerin A and novel analogues

Authors
Ragot, JP Steeneck, C Alcaraz, ML Taylor, RJK
Citation
Jp. Ragot et al., The synthesis of 1,8-dihydroxynaphthalene-derived natural products: palmarumycin CP1, palmarumycin CP2, palmarumycin C-11, CJ-12,371, deoxypreussomerin A and novel analogues, J CHEM S P1, (8), 1999, pp. 1073-1082
Citations number
39
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
8
Year of publication
1999
Pages
1073 - 1082
Database
ISI
SICI code
0300-922X(19990421):8<1073:TSO1NP>2.0.ZU;2-3
Abstract
Total syntheses of the title fungal metabolites are described via a route w hich utilises initial acetalisation with 1,8-dihydroxynaphthalene followed by elaboration of the ring A functionality. Novel analogues are also report ed. Structural clarification is provided for palmarumycin C-11, bipendensin and Sch 53,823.