Leptin receptor expression in human umbilical cord leucocytes

Citation
Ah. Garcia et al., Leptin receptor expression in human umbilical cord leucocytes, MED SCI RES, 27(4), 1999, pp. 231-232
Citations number
8
Categorie Soggetti
Medical Research General Topics
Journal title
MEDICAL SCIENCE RESEARCH
ISSN journal
02698951 → ACNP
Volume
27
Issue
4
Year of publication
1999
Pages
231 - 232
Database
ISI
SICI code
0269-8951(199904)27:4<231:LREIHU>2.0.ZU;2-2
Abstract
We have assessed the expression of leptin receptor on human umbilical cord blood leucocytes using flow cytometry, by a specific antibody, in 12 normal newborns (seven females and five males). The expression was significantly (P<0.0001) higher in polymorphonuclear cells (70 +/- 6%) as compared to mon ocytes (23 +/- 4%) and lymphocytes (16 +/- 4%). There was no correlation be tween the weight or the sex of the newborn and the effect of leptin or the expression of its receptor. Future studies should ascertain the type of lep tin receptor, its function and the role of this cytokine in cord blood cell s. Med Sci Res 27:231-232 (C) 1999 Lippincott Williams & Wilkins.