Exercise tolerance of patients under nasal intermittent positive pressure ventilation (nIPPV)

Citation
F. Bullemer et al., Exercise tolerance of patients under nasal intermittent positive pressure ventilation (nIPPV), MED KLIN, 94, 1999, pp. 29-31
Citations number
10
Categorie Soggetti
General & Internal Medicine
Journal title
MEDIZINISCHE KLINIK
ISSN journal
07235003 → ACNP
Volume
94
Year of publication
1999
Supplement
1
Pages
29 - 31
Database
ISI
SICI code
0723-5003(199904)94:<29:ETOPUN>2.0.ZU;2-#
Abstract
Background: There are only a few papers concerning with exercise tolerance of patients under nasal intermittent positive pressure ventilation (nIPPV). Patients and Method: Therefore since 1996 we routinely checked exercise to lerance of our nIPPV-patients when admitted to the hospital. Till March 199 7 we had carried out 138 6-minute walking tests (6-min WT) in 111 patients. Questions: Is there an improvement of exercise tolerance in the course of nIPPV-therapy? Are hypoxemia or hypercapnia occurring during exercise-test? Methods: The 6-min WT was performed after one practice walk. The patients got oxygen in case of a preexisting oxygen therapy or in case of an oxygen saturation below 85% before starting. Blood gas analyses were carried out b efore and after stopping the test. Oxygen saturation and heart rate were re gistered continuously. The distance walked was measured. Twenty-one patient s were tested before introducing nIPPV therapy and 3 months after home mech anical ventilation (HMV). Results: The average distance walked amounted only 283 +/- 82 m (norm in he althy persons: 800 m). pCO(2) decreased from 69 +/- 11 to 58 +/- 12 mm Hg, pCO(2) measured from 47 +/- 8 mm Hg. Oxygen saturation (SaO(2)) fell from 9 2 +/- 5 to 80 +/- 10%, heart rate increased from 104 +/- 18 to 130 +/- 23 b eats/min. The distance walked changed not significantly from 282 +/- 109 to 308 +/- 71 m. Six patients could be tested a 3rd time after 6 months HMV. The distance walked was 315 +/- 103 m (also no significant difference). Conclusions: Everyday activity can cause severe hypoxemia in nIPPV patients . Ambulatory oxygen therapy should be considered in each case. A significan t improvement of exercise tolerance under nIPPV therapy is not yet proven. Our data only show a tendency towards an increase.