Chiral synthons for carba-beta-D-ribonucleosides. Synthesis of carba-4-deoxypyrazofurin and isomeric carba-4-deaza-oxoformycin analogues

Authors
Mohar, B Kobe, J
Citation
B. Mohar et J. Kobe, Chiral synthons for carba-beta-D-ribonucleosides. Synthesis of carba-4-deoxypyrazofurin and isomeric carba-4-deaza-oxoformycin analogues, NUCLEOS NUC, 18(3), 1999, pp. 443-456
Citations number
23
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
3
Year of publication
1999
Pages
443 - 456
Database
ISI
SICI code
0732-8311(1999)18:3<443:CSFCSO>2.0.ZU;2-U
Abstract
Multi-step transformation of enantiomerically pure synthons, (1S,2S,3R,4R)- (4-hydroxymethyl-2,3-isopropylidenedioxy-1-cyclopentyl) methyl butyrate {(- )-5} and (1R,5R,6R,7S)-6,7-(isopropylidenedioxy)-3-oxabicyclo[3.2.1]octane- 2-one {(+)-11} into carba-4-deoxypyrazofurin 1 and isomeric carba-4-deaza-o xoformycin 2 analogues is presented.