NMR relaxation studies of GdDTPA in human serum albumin solution

Authors
Li, XY Li, XJ Zhang, SR Pei, FK
Citation
Xy. Li et al., NMR relaxation studies of GdDTPA in human serum albumin solution, POLYHEDRON, 18(5), 1999, pp. 695-697
Citations number
14
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
POLYHEDRON
ISSN journal
02775387 → ACNP
Volume
18
Issue
5
Year of publication
1999
Pages
695 - 697
Database
ISI
SICI code
0277-5387(1999)18:5<695:NRSOGI>2.0.ZU;2-Y
Abstract
The water relaxation enhancement behavior of GdDTPA in human serum albumin (HSA) solution has been studied. The results indicate that GdDTPA can integ rate noncovalently with HSA, mainly in forms of (GdDTPA)HSA and (GdDTPA),HS A, for which the apparent equilibrium constants are 0.05 mM(-1) and 0.02 mM (-2), respectively. (C) 1999 Elsevier Science Ltd. All rights reserved.