Associated coeliac disease and small-cell carcinoma of the esophagus

BACKGROUND: Coeliac disease is known to favor the development of neoplasia. Coeliac disease associated with small-cell carcinoma of the esophagus has not been reported to date. CASE REPORT: A 51-year-old man with coeliac disease known for several years was hospitalized for epigastric pain. Work-up led to the diagnosis of smal l-cell carcinoma of the lower esophagus. The patient was treated with 6 cyc les of chemotherapy using an etoposide-ciplatinum protocol associated with 60 Cy radiotherapy starting at the third cycle. The patient has remained in complete remission 2 years after diagnosis. DISCUSSION: Small-cell carcionoma of the esophagus is an exceptional findin g in a patient with coeliac disease. Chemotherapy associated with radiother apy has been successful in our patient.