Purpose: To compare the value of hydro-MRI with that of barium studies in p
atients with Crohn's disease. Materials and Methods: After an oral bowel op
acification using 1000 mi of a 2.5% mannitol solution, axial and coronal br
eathhold sequences (T2W HASTE +/- FS, contrast-enhanced T1W FLASH FS) were
acquired in 46 patients with Crohn's disease at 1,0T. The findings of hydro
-MRI were compared with those of barium studies. Results: In the stomach an
d the small bowel, hydro-MRI and barium studies demonstrated similar number
s of Crohn's involvements (39 vs. 36); in the colon, hydro-MRI showed clear
ly more affections (23 vs. 10). Hydro-MRI showed 12.7cm of inflamed bowel p
er patient, on average (barium studies: 10,4 cm; p = 0,004). There was a go
od agreement between the two methods regarding the assessment of the extent
of Crohn's disease and the severity of bowel stenoses (r=0.89 and 0.88, re
spectively). Conclusions: For the assessment of Crohn's disease, hydro-MRI
is preferable to the barium study because of the superior imaging quality a
nd the lack of radiation exposure.