ORGANOPHOSPHATE EFFECTS ON ANTIOXIDANT SYSTEM OF CARP (CYPRINUS-CARPIO) AND CATFISH (ICTALURUS-NEBULOSUS)

The effect of the organophosphate insecticide Dichlorvos on antioxidan t enzymes and other oxidative and redox parameters of carp (Cyprinus c arpio L.) and catfish (Ictalurus nebulosus) were studied. Changes in s uperoxide dismutase, catalase, glutathione peroxidase, and in the case of carp acetylcholinesterase activities were studied in tissue homoge nates. Other parameters studied: changes of lipid peroxidation, reduce d glutathione and the amounts of two radicals, superoxide and hydroxyl radicals are compared. Our results showed that the organophosphate te sted, besides its inhibitory effect on acetylcholinesterase-or togethe r with it-induces changes characteristic of ''oxidative stress.'' (C) Elsevier Science Inc.