Pancreatic ascites can occur in association with the rupture of a pseudocys
t or the disruption of a pancreatic duct during the natural course of chron
ic pancreatitis. We report herein the successful treatment of three patient
s with pancreatic ascites by performing a surgical procedure after 4-6 week
s of total parenteral nutrition (TPN) pro, ed ineffective. The principles o
f our surgical procedure for pancreatic ascites are as follows: (1) minimum
pancreatic tissue is resected; (2) surgical intervention to repair leaking
sites is not necessary; (3) pancreatic duct drainage is facilitated by an
intestinal ROUX-en-Y loop; (4) An external drainage tube is inserted throug
h the Ronx-en-Y loop into the main pancreatic duct. All three patients who
underwent our surgical procedure had a good outcome. Although the mean foll
ow-up time is still only 18.3 months, their condition has improved, with no
evidence of recurrent ascites, Thus, our surgical procedure should be cons
idered as an appropriate treatment for pancreatic ascites because it can be
applied for all types of leakage, including leakage from the posterior wal
l of pancreas; it preserves pancreatic function, especially endocrine funct
ion; and it enables preservation of the spleen.