Citation
Kj. Hwang et Ts. Lee, A practical synthesis of N-acetyl-5-methoxytryptamine (melatonin), SYN COMMUN, 29(12), 1999, pp. 2099-2104
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911
→ ACNP
Volume
29
Issue
12
Year of publication
1999
Pages
2099 - 2104
Database
ISI
SICI code
0039-7911(1999)29:12<2099:APSON(>2.0.ZU;2-#
Abstract
The pineal hormone melatonin is conveniently prepared in a. simple one pot
operation by treating 4-methoxyphenylhydrazine hydrochloride(6) with acetic
anhydride and 4-aminobutyraldehyde dimethylacetal(4) in a mixed solvent sy
stem of acetic acid / ethanol / water.