Improved syntheses of fluorinated tertiary butylamines

Authors
Ok, D Fisher, MH Wyvratt, MJ Meinke, PT
Citation
D. Ok et al., Improved syntheses of fluorinated tertiary butylamines, TETRAHEDR L, 40(20), 1999, pp. 3831-3834
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
20
Year of publication
1999
Pages
3831 - 3834
Database
ISI
SICI code
0040-4039(19990514)40:20<3831:ISOFTB>2.0.ZU;2-X
Abstract
Two new and efficient methods using cyclic sulfamidate and nitrone chemistr y were developed for the synthesis of the sterically congested 1,1-dimethyt -2-fluoroethylamine (1), 2-fluoro-1-(fluoromethyl)-1-methyl ethylamine (2) and 2-fluoro-1,1-bis-(fluoromethyl)-ethylamine (3). (C) 1999 Elsevier Scien ce Ltd. All rights reserved.