A volumetric study of molecular inclusion by alpha-cyclodextrin

Authors
Isaacs, NS Young, DJ
Citation
Ns. Isaacs et Dj. Young, A volumetric study of molecular inclusion by alpha-cyclodextrin, TETRAHEDR L, 40(20), 1999, pp. 3953-3956
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
20
Year of publication
1999
Pages
3953 - 3956
Database
ISI
SICI code
0040-4039(19990514)40:20<3953:AVSOMI>2.0.ZU;2-F
Abstract
The reaction volume (Delta (V) over bar(c-->0)) associated with inclusion o f 3-nitrophenol by alpha-cyclodextrin was determined by densitometry to be -9 cm(3) mol(-1) while the corresponding value for encapsulation of methyl orange by two molecules of alpha-cyclodextrin is +27 cm(3) mol(-1). These v olume changes can be interpreted in terms of displacement of solvent from t he cavity of alpha-cyclodextrin and/or changes in solvation of the "guest" molecule. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.