The objective of this study was to determine the proportion of Massachusett
s Medicare patients who received prophylaxis for venous thromboembolism fol
lowing colectomy, hysterectomy or total hip arthroplasty. The sample frame
was all 90 Massachusetts acute care hospitals, and the time frame was 1 Apr
il to 30 September 1994. The patients discharged with an International Clas
sification of Disease (ICD-9-CM) discharge diagnostic code (recorded in the
Massachusetts Medicare Claims Database) for colectomy, hysterectomy or tot
al hip arthroplasty were used to Identify the larger patient population. Th
e sample population comprised 1397 patients randomly selected from the targ
et population, including 467 total hip arthroplasties, 474 colectomies, and
456 hysterectomies. Medical records were reviewed by trained nurse abstrac
tors who collected information on the use of prophylaxis for venous thrombo
embolism. Prophylaxis for venous thromboembolism was employed by surgeons p
ractising in Massachusetts hospitals in 93 per cent of total hip arthroplas
ty cases (regional variation 85-98 per cent), 84 per cent of colectomies (r
egional variation 57-93 per cent), 66 per cent of hysterectomies (regional
variation 35-71 per cent), and in 87 per cent of the subset of 111 hysterec
tomies with malignancy (regional variation 25-100 per cent). The results of
this statewide study demonstrated significant regional and hospital-to-hos
pital variation in use of prophylaxis for venous thromboembolism following
major surgery. A lower rare of prophylaxis use was observed in hospitals wi
th fewer than 200 beds and in hospitals that did not have teaching programm
es. Hospitals with below-average rates of prophylaxis were targeted fur int
ensive quality improvement;interventions.