CHARACTERIZATION OF AN IMIDAZOLIUM COMPOUND FORMED BY REACTION OF METHYLGLYOXAL AND N-ALPHA-HIPPURYLLYSINE

Authors
BRINKMANN E WELLSKNECHT KJ THORPE SR BAYNES JW
Citation
E. Brinkmann et al., CHARACTERIZATION OF AN IMIDAZOLIUM COMPOUND FORMED BY REACTION OF METHYLGLYOXAL AND N-ALPHA-HIPPURYLLYSINE, Journal of the Chemical Society. Perkin transactions. I, (22), 1995, pp. 2817-2818
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
22
Year of publication
1995
Pages
2817 - 2818
Database
ISI
SICI code
0300-922X(1995):22<2817:COAICF>2.0.ZU;2-U
Abstract
The 1,3-di-N-alpha-hippuryllysino-4-methylimidazolium salt 6 has been identified as a major product of reaction of the alpha-dicarbonyl comp ound, methylglyoxal 1, with the lysine derivative, N-alpha-hippuryllys ine (N-alpha-benzoylglycyllysine) 2, in phosphate buffer at neutral pH , suggesting a mechanism for crosslinking of protein by 1 and related dicarbonyl compounds during the Maillard reaction.