Intravenous leiomyomatosis with cardiac extension is a rare entity. The cas
e of a 49-year-old patient is described: she was operated on for intracaval
intra-atrial leiomyomatosis. After an incomplete procedure (the tumour app
eared not totally resectable), the patient was treated for a period of thre
e years with a GnRH-analogue, whereafter the patient was doing clinically w
ell and the tumour, although it regained some growth, was in a stable situa
tion. This new strategy seems of certain importance to the surgeon, as it c
arries an alternative to a high-risk reoperation. To our knowledge, this is
the first description of such a combined therapeutical approach.