Maintaining the vaccine cold chain is an essential part of a successful imm
unization programme, but in developed countries faulty procedures may occur
more commonly than is generally believed. A survey was conducted in a heal
th district in central Italy to assess the methods of vaccine transportatio
n and storage. Of 52 primary vaccination offices inspected, 39 (76.5%) had
a refrigerator for vaccine storage but only 17 (33.3%) kept records of rece
ived and stored doses. None of the seven main offices selected for monitori
ng had a maximum and minimum thermometer and none monitored the internal te
mperature of the refrigerator. Moreover, other faulty procedures, such as t
he storage of food and laboratory specimens in vaccine refrigerators and th
e storage of vaccines on refrigerator door shelves, indicated that the know
ledge and practice of vaccine storage and handling were often inadequate.