We report a case of diffuse necrobiosis lipoidica (NL) which first appeared
on the legs and scrotum, before gradually spreading across the back and ar
ms; the patient also suffered from diabetes mellitus, and the NL lesion beg
an to disappear as the diabetes mellitus was controlled. The possible contr
ibution of various glycation and glycoxidation products of collagen to the
pathogenesis of NL is discussed.