This article is a discussion of occupational cancer in italy. The introduct
ion provides the necessary context of Italian industrialization and occupat
ional health regulation. This is followed by a review of Italian epidemiolo
gic studies of occupational cancer risks considered in terms of relative me
asures of risk and attributable risk of carcinogenic agents or exposure cir
cumstances. We attempt to establish the number of workers exposed to carcin
ogens in Italy and the intensity of their exposures. Finally, the Italian s
ystem of compensation for occupational cancer is discussed. Several cohort
and case-control studies have addressed the issue of occupational risks, mo
stly among male workers. The results of these studies suggest that the grow
ing incidence of and mortality by mesothelioma is explained by the widespre
ad and intense exposure to asbestos in some Italian industrial settings. A
high attributable risk of lung tumors among male populations in industrial
areas of northern Italy is explained by occupational exposures. However, in
sufficient data are available for clear definition of the extent and intens
ity of occupational exposure to carcinogenic substances. In Italy, we must
prioritize and maximize resources in occupational cancer epidemiology and r
evitalize the role of national institutions. Recent legislation has establi
shed new regulations on the handling of carcinogenic substances in industri
al settings, a new list of occupational diseases, and a national registry o
f mesothelioma linked to asbestos exposure. These legislative changes are e
xpected to have positive effects.