Prevalence of diabetic eye disease in an inner city population: the Liverpool Diabetic Eye Study

Purpose To measure the population prevalence of diabetic eye disease in an inner city setting. Methods As part of a systematic screening programme all adult diabetic pati ents in four general practices were invited to attend for slit-lamp biomicr oscopy by a retinal specialist. Data on non-attenders were available from c ommunity-based photography. Results Of 395 diabetic patients identified, 326 attended biomicroscopy wit h photographic data available on a further 31, giving a 90% compliance rate . Point prevalence of diabetes in the target population was 12.4/ 1000. Dem ographic data included: mean age 60 years (range 13-92 years); type of cont rol: type I 49, type II insulin-requiring (IR) 40, type II non-insulin-requ iring (NIR) 268. Prevalences were as follows: any retinopathy: of all diabe tic patients 33.6%, type I 36.7%, type II IR 45.0%, type II NIR 31.3%; prol iferative/ advanced: all 1.1%, type I 2.0%, type IT IR 0, type II NIR 1.1%; clinically significant macular oedema: all 6.4%, type I 2.3%, type II IR 1 6.2%, type II NIR 5.7%. The percentage of patients with retinopathy requiri ng follow-up by an ophthalmologist was 4.5%, and 9.2% had macular exudates within 1 disc diameter of fixation or significant circinate maculopathy. Si ght-threatening diabetic eye disease (STED) was found in 13.4%. A visual ac uity of less than or equal to 6/24 in the better eye occurred in 12 (3.4%) patients and of less than or equal to 6/60 in the better eye in 3 (0.8%). Conclusions Compared with previous population studies, prevalences appear t o have declined in type I, but remain high in type II diabetic patients and especially in those requiring insulin.