Isolated magnesium malabsorption is a rare disorder, which bas been describ
ed in no more than 30 patients worldwide. Patients with this disorder typic
ally present with convulsion and diarrhea in early infancy. Hypomagnesemia
and hypocalcemia were found in a 35-year-old man with muscle cramps, who ba
d been diagnosed as primary hypoparathyroidism. Oral magnesium therapy corr
ected the low serum calcium, magnesium and parathyroid hormone levels. We r
eport an atypical case of isolated magnesium malabsorption in an adult.