Borrowing from evolutionary biology, existentialism, developmental psycholo
gy, and social learning theory, an integrated model of human behavior is ap
plied to several forms of self-destructive behavior, to include anorexia ne
rvosa, suicide, substance abuse, and pathological gambling. It is argued th
at self-destructive behavior is a function of how the individual psychologi
cally construes survival and copes with perceptions of isolation and separa
tion from the environment. The paradox of self destructive behavior in orga
nisms motivated by self-preservation is resolved by caking note of the fact
that self-destruction seems from people's efforts to survive psychological
ly and resolve the subject-object duality, even when this places their phys
ical well-being in jeopardy.