K. Oberholzer et al., PNEUMOMEDIASTINUM AND PNEUMOPERICARDIUM DUE TO MALIGNANT SUBCARINAL LYMPHADENOPATHY - CT DEMONSTRATION, European radiology, 7(4), 1997, pp. 583-585
A 52-year-man had been treated for oral cancer T3 N0 M0 by radical sur
gery, neck dissection on the right and cervical irradiation (60 Gy). T
wo months after therapy he presented with dysphagia and hemoptysis. Ad
mission chest X-ray revealed a pneumopericardium. It was caused by a b
ronchomediastinal fistula due to necrotic metastatic lymph nodes as sh
own by CT, which also revealed a concomitant pneumomediastinum. The pa
tient died 10 days later from pneumonia. The CT findings were confirme
d at autopsy. We conclude that malignant mediastinal lymphadenopathy i
s a potential cause of pneumopericardium and pneumomediastinum.