A case of chorea-acanthocytosis (CA) syndrome is described. The presence of
acanthocytes has usually been considered an important diagnostic marker of
CA. However, it is not specific and other neurological diseases have to be
considered. In the present report we rule out other diagnostic possibiliti
es and show that the acanthocytes in the peripheral blood smears can appear
even later during the course of the disease. (C) 1999 Elsevier Science B.V
. All rights reserved.