Writing hand preference is a prominent functional asymmetry, but biomechani
cal factors may also contribute to any kinematic differences in the quality
of handwriting movements performed by either hand. Eighteen dextral partic
ipants used a noninking pen with their right or left hand to write cursive
letter is, inverted Is, and their mirror images (to control for biomechanic
al differences) on a graphics tablet. Kinematic analysis of the scaling, co
nsistency, efficiency, and shape of writing stroke trajectories revealed fu
nctional asymmetries between hands. The right hand was faster and produced
more efficient strokes, which were of more consistent length, duration, and
peak velocity. Differences between hands do not simply reflect biomechanic
al factors; therefore, the documentation of any functional asymmetries may
allow their subsequent use as markers of underlying pathology in conditions
such as schizophrenia.