Structure elucidation by ion trap sequential mass spectrometry of radical cations formed in low-energy charge-exchange reactions

A low-pressure, low-energy charge-exchange reaction with furan is shown to be a convenient method for generating the requisite intense ion signals fro m molecular radical cations of dextromethorphan for MSn (sequential, produc t-ion scans) analysis. Little fragmentation results, concentrating ion curr ent in the molecular species and facilitating MSn probing. Results for the odd-electron species are shown to provide some unique information compared to electrospray ionization MSn of the even-electron, protonated molecule of dextromethorphan, Copyright (C) 1999 John Wiley & Sons, Ltd.