Background: Lymphadenopathy in children can be a challenging clinical situa
tion that requires a careful approach. Aim: To report the experience with f
ine needle aspiration biopsy for the diagnosis of lymphadenopathy. Patients
and methods: Analysis of 95 pediatric patients, aged 3 months to 19 years
old, referred by primary care physicians for the study of lymphadenopathy.
All were subjected to a complete medical examination, laboratory tests and
fine needle aspiration biopsy. Results: Seventy seven per cent of enlarged
lymph nodes were located in the neck. Fine needle aspiration showed a hyper
plastic adenitis in 44 patients (46%). In 13 patients, an infectious adenit
is, sometimes suppurated was observed. In 9 patients a BCG or tuberculous a
denitis with caseum was found. In 13 patients, citology disclosed a non lym
phatic mass, in four patients a Hodgkin discase and in one, malignant cells
of unknown origin. Four patients had a normal lymph node and in 2 the samp
le was insufficient for cytological analysis. Conclusions: Fine needle aspi
ration biopsy is a simple and safe diagnostic method for lymphadenopathy in
children.