Development of novel reactions using hypervalent iodine(III) reagents: Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (+/-)-makaluvamine F

Authors
Kita, Y Egi, M Takada, T Tohma, H
Citation
Y. Kita et al., Development of novel reactions using hypervalent iodine(III) reagents: Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (+/-)-makaluvamine F, SYNTHESIS-S, (5), 1999, pp. 885-897
Citations number
112
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
5
Year of publication
1999
Pages
885 - 897
Database
ISI
SICI code
0039-7881(199905):5<885:DONRUH>2.0.ZU;2-Y
Abstract
Novel and efficient intramolecular nucleophilic substitution reactions of p henol ethers using activated hypervalent iodine species have been developed and their application to the total synthesis of strongly cytotoxic makaluv amine F (1), a member of sulfur-containing pyrroloiminoquinone marine produ cts, is described.