Met. Willems et al., Swelling of sarcoplasmic reticulum in the periphery of muscle fibres afterisometric contractions in rat semimembranosus lateralis muscle, ACT PHYSL S, 165(4), 1999, pp. 347-356
The decline in isometric force, swelling of sarcoplasmic reticulum and loss
of desmin was measured in semimembranosus lateralis muscle of male Wistar
rats immediately after a short series of brief (500 ms) maximal isometric c
ontractions. For the active muscle, the series ended below (protocol A) and
just over muscle optimum length (protocol AA). in one protocol, the muscle
remained passive and was extended to lengths just over muscle optimum leng
th (protocol P). After all experimental protocols, no loss of desmin was ob
served and sarcomere appearance was normal. Protocol A produced swelling (8
7%) of the sarcoplasmic reticulum but no decline in isometric force. Protoc
ol AA produced larger swelling (147%) of the sarcoplasmic reticulum and an
isometric force decline (<49%) at short muscle lengths. Swelling of sarcopi
asmic reticulum was observed mainly in the periphery of muscle fibres. Prot
ocol P did not result in swelling of the sarcoplasmic reticulum and isometr
ic force decline. It is concluded that swelling of the sarcoplasmic reticul
um in the periphery of muscle fibres after brief maximal isometric contract
ions is associated with muscle force and not muscle length.