U. Hahn et al., Renal MR angiography at 1.0 T: Three-dimensional (3D) phase-contrast techniques versus gadolinium-enhanced 3D fast low-angle shot breath-hold imaging, AM J ROENTG, 172(6), 1999, pp. 1501-1508
Citations number
37
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
OBJECTIVE, The purpose of this study was to evaluate the diagnostic usefuln
ess of three different MR angiographic techniques at 1.0 T.
SUBJECTS AND METHODS. In 22 patients with renal artery stenosis confirmed a
t intraarterial catheter angiography, we also performed unenhanced and gado
linium-enhanced three-dimensional phase-contrast MR angiography and gadolin
ium-enhanced single breath hold three-dimensional fast low-angle shot MR an
giography. We determined circulation time to optimize signal acquisition in
gadolinium-enhanced breath-hold MR angiography after bolus injection of co
ntrast material.
RESULTS. Sensitivity, defined as the detection of a hemodynamically signifi
cant stenosis (>50% luminal narrowing), was 85% for enhanced phase-contrast
MR angiography, 91% for gadolinium-enhanced MR angiography, and 95% for un
enhanced phase-contrast MR angiography. The combination of unenhanced phase
-contrast MR angiography and gadolinium-enhanced MR angiography yielded 100
% sensitivity for hilar artery stenoses. There were 13 false-positive findi
ngs with unenhanced phase-contrast MR angiography, 10 with enhanced phase-c
ontrast MR angiography, and four with gadolinium-enhanced MR angiography (s
pecificity: 38%, 52%, and 79%, respectively). Accessory renal arteries were
not seen on unenhanced or enhanced phase-contrast MR angiography (0/8 pati
ents) but were detected with gadolinium-enhanced MR angiography in five of
the eight patients. Interobserver agreement (kappa = .62) was best with gad
olinium-enhanced MR angiography. The quality of the images was unsatisfacto
ry for adequate evaluation of segmental renal arteries with all three MR an
giographic techniques.
CONCLUSION. A combination of unenhanced phase-contrast MR angiography and g
adolinium-enhanced MR angiography at 1.0 T proved useful as a screening pro
tocol for renal artery stenosis.