This research addressed the question of whether relationships exist between
personality dimensions, antisocial behavior and alcohol or other substance
misuse (AOSM) in adolescents and in their fathers and mothers, who often a
lso have histories of AOSM. One hundred male adolescents (mean age 15.8 yea
rs) entering a residential treatment center for youths with AOSM, their mot
hers (n = 88, mean age 39.4 years) their fathers (n = 36, mean age 44.9 yea
rs), and community controls (n = 100 adolescents, mean age 16.5 years; n =
36 mothers, mean age 43.8 years; n = 87 fathers, mean age 45.9 years) were
recruited. All participants completed a personality questionnaire and were
interviewed on several measures, including structured interviews for sychop
athology and substance misuse. The findings indicated that novelty seeking
(NS) one of the Personality dimensions, was significantly correlated with s
ubstance misuse in adolescent probands, adolescent controls, and proband fa
thers and mothers, but not in control fathers and mothers. Regression analy
ses that included conduct disorder (CD) or antisocial personality disorder
(APD) symptoms indicated that both NS and CD or APD symptoms made significa
nt contributions to the prediction of substance misuse in treatment group p
robands and in their fathers and mothers. The findings further suggest that
NS and antisocial behaviors contribute independently to substance misuse i
n severely impaired adolescents and their fathers, but not in their mothers
.