Management of cancer in pregnancy: A case of Ewing's sarcoma of the pelvisin the third trimester

Ewing's sarcoma of the pelvic bones was diagnosed in a 21-year childbearing woman, raising major medical and ethical problems. The diagnostic and ther apeutic approaches during the sixth month of gestation were tailored in ord er to cure the patient and avoid unnecessary toxicity to the fetus. Ancilla ry tests included ultrasound and MRI studies of the pelvis. Ifosfamide and adriamycin, premedicated by granisetron, were administered during gestation , and were found to be safe. Cesarean section was the preferred way of deli very since the tumor involved the pelvic bones. The outcome was a disease-f ree patient and a small healthy baby who is now two years of age.