ESPript: analysis of multiple sequence alignments in PostScript

Motivation: The program ESPript (Easy Sequencing in PostScript) allows the rapid visualization, via PostScript output, of sequences aligned with popul ar programs such as CLUSTAL-W or GCG PILEUP. It can read secondary structur e files (such as that created by the program DSSP) to produce a synthesis o f both sequence and structural information. Results: ESPript can be run via a command file or a friendly html-based use r interface. The program calculates an homology score by columns of residue s and can sort this calculation by groups of sequences. It offers a palette of markers to highlight important regions in the alignment. ESPript can al so paste information on residue conservation into coordinate files, for sub sequent visualization with a graphics program.