Citation
Bm. Kwon et al., Acyl-CoA: Cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins, BIOORG MED, 9(10), 1999, pp. 1375-1378
Citations number
12
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X
→ ACNP
Volume
9
Issue
10
Year of publication
1999
Pages
1375 - 1378
Database
ISI
SICI code
0960-894X(19990517)9:10<1375:ACAIAO>2.0.ZU;2-A
Abstract
Ginseng sapogenins were produced from ginseng saponins, isolated from Korea
n ginseng roots. Ginseng saponins very mildly inhibited acyl-CoA:cholestero
l acyltransferase (ACAT) in vitro, however, the sapogenins showed strong in
hibitory activity on microsomal ACAT. Therefore, the sapogenins will be one
of key ingredients of ginseng affected a lowering of the serum total chole
sterol level. (C) 1999 Elsevier Science Ltd. All rights reserved.